Shortly after finishing Crysis across three screens, I promptly got to work on Oblivion.
Oblivion was not difficult to use SoftTH v1.07b to span 3 screens, no configuration changes were needed, although I prefer changing the side monitors to run in 32bit rather than 16bit. This can be done with the following setting secondaryFormat=RGB32
Bonus: Triple Screen Ending (Spoilers)
This is an awesome website on Multimonitors. I noticed that you have a lot of Panoramic games on here, but no videos on the business and multi-tasking aspects of Multimonitors. Here is a cool youtube video I found that shows the other side of multiple monitors. I love the versatility of being one large screen or multiple independent screens.
http://www.youtube.com/watch?v=j_avGStqZOI